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Home / About Us / Lab Members / Filip Van Petegem
Filip Van Petegem, Ph.D.
 
 

Postdoctoral Fellow
Dan Minor Lab
UCSF

Phone: 415-514-2836

 
Education
 

1994-1996: Candidate Chemistry, Ghent University, Belgium

1996-1998: Licensee Biochemistry, Ghent University, Belgium

1998-2002: Ph.D. Biochemistry, Ghent University, Belgium; P.I.: Prof. Jozef Van Beeumen

2002-now: Postdoc UCSF, CVRI, San Francisco; P.I.: Prof. Dan Minor

 
Awards & Honors
 

Doctoral Fellowship: "Fonds voor wetenschappelijk onderzoek Vlaanderen" (Fund for scientific research, Flanders)

Postdoctoral Fellowship: American Heart Association

Prize Innogenetics 1998

 
Publications
 

Van Petegem, F. and Minor, D.L., Jr., The structural biology of voltage-gated calcium channel function and regulation. Biochemical Society Transactions (in press)

Van Petegem, F., Chatelain, F.C., and Minor, D.L., Jr. Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex. Nature Structural and Molecular Biology 12 1108-1115 (2005)

Dumortier C, Fitch J, Van Petegem F, Vermeulen W, Meyer TE, Van Beeumen JJ, Cusanovich MA. (2004) Protein dynamics in the region of the sixth ligand methionine revealed by studies of imidazole binding to Rhodobacter capsulatus cytochrome c2 hinge mutants. Biochemistry 43, 7717-7724.

De Vos D, Van Petegem F, Remaut H, Legrain C, Glansdorff N, Van Beeumen JJ. (2004) Crystal structure of T state aspartate carbamoyltransferase of the hyperthermophilic archaeon Sulfolobus acidocaldarius. J Mol Biol. 339,887-900.

Van Petegem F, Clark KA, Chatelain FC, Minor DL Jr. (2004) Structure of a complex between a voltage-gated calcium channel beta-subunit and an alpha-subunit domain. Nature 429, 671-675.

Aghajari N, Van Petegem F, Villeret V, Chessa JP, Gerday C, Haser R, Van Beeumen J. (2003)
Crystal structures of a psychrophilic metalloprotease reveal new insights into catalysis by cold-adapted proteases. Proteins 50, 636-647.

Van Petegem F, Collins T, Meuwis MA, Gerday C, Feller G, Van Beeumen J. (2003) The structure of a cold-adapted family 8 xylanase at 1.3 A resolution. Structural adaptations to cold and investigation of the active site. J Biol Chem. 278, 7531-7539

Van Petegem F, Collins T, Meuwis MA, Gerday C, Feller G, Van Beeumen J. (2003) Crystallization and preliminary X-ray analysis of a xylanase from the psychrophile Pseudoalteromonas haloplanktis. Acta Crystallogr D Biol Crystallogr. 58, 1494-1496.

Van Petegem F, Vandenberghe I, Bhat MK, Van Beeumen J. (2002) Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus. Biochem Biophys Res Commun. 296, 161-166.

Vergauwen B, Van Petegem F, Remaut H, Pauwels F, Van Beeumen JJ. (2002) Crystallization and preliminary X-ray crystallographic analysis of glutathione amide reductase from Chromatium gracile. Acta Crystallogr D Biol Crystallogr. 58, 339-340

Van Petegem F, Contreras H, Contreras R, Van Beeumen J. (2001)
Trichoderma reesei alpha-1,2-mannosidase: structural basis for the cleavage of four consecutive mannose residues. J Mol Biol. 312, 157-165.

Georlette D, Jonsson ZO, Van Petegem F, Chessa J, Van Beeumen J, Hubscher U, Gerday C. (2000)
A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperatures. Eur J Biochem. 267, 3502-3512.

 
 
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