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| Ashrafi, Kaveh |
| Barber, Diane L |
| Bernstein, Harold S. |
| Black, Brian L |
| Blanc, Paul D |
| Boushey, Homer A |
| Broaddus, V Courtney |
| Brown, James K |
| Caughey, George H |
| Chapman, Harold A |
| Charo, Israel F |
| Chatterjee, Kanu |
| Chuang, Pao-Tien |
| Clyman, Ronald I |
| Conklin, Bruce R |
| Coughlin, Shaun R |
| Derynck, Rik M |
| Dobbs, Leland G |
| Eisner, Mark D |
| Engel, Joanne N |
| Erle, David J |
| Fahy, John Vincent |
| Farese, Robert V |
| Fielding, Christopher J |
| Fielding, Phoebe |
| Fineman, Jeffrey R |
| Glantz, Stanton A |
| Grossman, William |
| Hawgood, Samuel |
| Ingraham, Holly A |
| Jan, Lily Y |
| Kan, Yuet W |
| Kane, John P |
| Kornberg, Thomas B |
| Kurtz, Theodore W |
| Kwok, Pui-Yan |
| Lazarus, Stephen C |
| Malloy, Mary J. |
| Martin, Gail R |
| Matthay, Michael A |
| Mcdonald, Donald M |
| Mikawa, Takashi |
| Minor, Daniel L |
| Mostov, Keith E |
| Nadel, Jay A |
| Ordahl, Charles P |
| Pitas, Robert E |
| Reiter, Jeremy F. |
| Rosen, Steven D |
| Shaw, Robin M. |
| Sheppard, Dean |
| Simpson, Paul C |
| Stainier, Didier Y. R. |
| Wang, Rong |
| Weiner, Orion D |
| Weisgraber, Karl H |
| Weiss, Arthur |
| Weiss, Ethan J |
| Werb, Zena |
| Wiener-Kronish, Jeanine |
| Young, William L |
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CVRI Scientists
Mark D Eisner, A.B., M.D. , M.P.H.
Assoc Professor In Residence
Research Interests:
Title: Epidemiology and health outcomes of obstructive lung disease
Key words: asthma, COPD, epidemiology, indoor air pollution, environmental tobacco smoke, secondhand smoke, passive smoking, disability, severe asthma, health outcomes
Summary:
The burden of obstructive lung disease, which includes asthma and Chronic Obstructive Pulmonary Disease (COPD), continues to increase in the U.S. and around the world. My research program in obstructive lung disease has two central areas: (1) to identify factors that negatively affect the health of adults with asthma, especially those with severe disease and (2) to elucidate how disability develops in COPD. These two parallel lines of investigation are distinct, but mutually reinforcing. In asthma, I am studying how smoking, secondhand smoke exposure, and other environmental exposures affect the health outcomes of adults with asthma. I am also interested in how the process of health care, which includes specialist care, influences health among adult asthmatics. In addition, I am studying how patient-level factors, such as depression and quality of life, impact asthma-related health.
A central goal of my research in obstructive lung disease is to prevent deterioration of health status and the development of disability. In a large cohort of patients with COPD, I will elucidate the disablement process in COPD. I have previously shown that adults with COPD have a 10-fold higher risk of disability than members of the general population. However, the current understanding of how disability develops in COPD is limited. In particular, pulmonary function impairment and clinical staging systems do not predict who will develop disability. To elucidate the disablement process, I have established a population-based prospective cohort study of 1200 COPD patients to test a specific conceptual model of how disability develops in COPD. The goal is to provide a scientific basis for the screening and prevention of COPD-related disability.
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