Ashrafi, Kaveh
Barber, Diane L
Bernstein, Harold S.
Black, Brian L
Blanc, Paul D
Boushey, Homer A
Broaddus, V Courtney
Brown, James K
Bruneau, Benoit G
Caughey, George H
Chapman, Harold A
Charo, Israel F
Chatterjee, Kanu
Chuang, Pao-Tien
Clyman, Ronald I
Conklin, Bruce R
Coughlin, Shaun R
Derynck, Rik M
Dobbs, Leland G
Eisner, Mark D
Engel, Joanne N
Erle, David J
Fahy, John Vincent
Farese, Robert V
Fielding, Christopher J
Fielding, Phoebe
Fineman, Jeffrey R
Glantz, Stanton A
Grossman, William
Hawgood, Samuel
Ingraham, Holly A
Jan, Lily Y
Kan, Yuet W
Kane, John P
Kornberg, Thomas B
Kurtz, Theodore W
Kwok, Pui-Yan
Lazarus, Stephen C
Malloy, Mary J.
Martin, Gail R
Matthay, Michael A
Mcdonald, Donald M
Mikawa, Takashi
Minor, Daniel L
Mostov, Keith E
Nadel, Jay A
Ordahl, Charles P
Pitas, Robert E
Reiter, Jeremy F.
Rosen, Steven D
Scheinman, Melvin M
Shaw, Robin M.
Sheppard, Dean
Simpson, Paul C
Stainier, Didier Y. R.
Wang, Rong
Weiner, Orion D
Weisgraber, Karl H
Weiss, Arthur
Weiss, Ethan J
Werb, Zena
Wiener-Kronish, Jeanine
Young, William L

CVRI Scientists

Robert V. Farese, Jr., M.D.
Senior Scientist, J. David Gladstone Institutes, Professor of Medicine and of Biochemistry & Biophysics

Research Interests:
Cell Biology of Energy Metabolism

Summary:
"The ability of cells to store and utilize energy in a regulated manner is fundamental to life, and abnormalities in energy metabolism play a central role in diseases such as obesity, type two diabetes, neurodegeneration, and aging. Our laboratory is interested in cellular energy homeostasis, focusing on three interrelated areas of research: the cell biology of lipid storage, the enzymes of neutral lipid synthesis, and energy metabolism in neurons. Our approaches are basic, emphasizing biochemistry and cellular biology, with specific hypothesis testing in model organisms such as flies and mice. Our group has two new areas of investigation: 1) the cell biology of lipid droplet formation and utilization, and 2) neuron cell biology and neurodegeneration, with a focus on frontotemporal dementia. For more information on our laboratory, please visit our laboratory web site (www.gladstone.ucsf.edu/gladstone/files/farese/HomePage/index.html)."

CVRIHead